Fibrodysplasia Ossificans Progessiva


Mutations in the ACVR1 gene.

ACVR1 gene provides instructions for producing a member of a protein family called bone morphogenetic protein.

How do we get F.O.P?

It can be inherited in an autosomal dominant pattern or it could occur randomly while in the womb.


Malformed big toes and painful tumor like swellings on the head, neck, and/or back.


You can be given systemic steroids but there is no proven solution to treat F.O.P

Want to find out more about F.O.P? Look here! ghr.nlm.nuh.gov/condition/disability/types/fop.php