What is Porphyria?
Porphyria is a group of disorders caused by abnormalities in the chemical steps that lead to heme production. Heme is a vital molecule for all of the body's organs,heme is a component of several iron-containing proteins called hemoproteins, including hemoglobin (the protein that carries oxygen in the blood).
How can people inheritate Porphyria?
As you see in the picture the hand are really damaged and they also look like they been put in fire and burned. But what actually happend was the Porphyria
This little girl's skin and face is filled with Porphyria . It looks like she has red spots on her face and all over her hands
Most porphyrias are inherited disorders, one type of porphyria is most often an acquired disorder.
- Drugs such as barbiturates, tranquilizers, birth control pills, and sedatives
- Drinking alcohol, especially to excess
- Excess iron
- Emotional and physical stress
- Menstrual hormones
- Sun exposure
What does Porphyria do?
The porphyrias can also be split into erythropoietic and hepatic types, depending on where damaging compounds called porphyrins precursors first build up in the body. Health problems associated with erythropoietic porphyrias include a low number of red blood cells (anemia) and enlargement of the spleen. The other types of porphyrias are considered hepatic porphyrias. In erythropoietic porphyrias, these compounds originate in the bone marrow. The other types of porphyrias are considered hepatic porphyrias. In these disorders, porphyrins and porphyrin precursors originate primarily in the liver, leading to abnormal liver function and an increased risk of developing liver cancer.
Environmental factors can strongly influence the occurrence and severity of signs and symptoms of porphyria. Alcohol, smoking, certain drugs, hormones, other illnesses, stress, and dieting or periods without food (fasting) can all trigger the signs and symptoms of some forms of the disorder. Additionally, exposure to sunlight worsens the skin damage in people with cutaneous originate primarily in the liver, leading to abnormal liver function and an increased risk of developing liver cancer.