Rough Endoplasmic Reticulum

By: Lily Kraus

Rough Endoplasmic Reticulum

  • Rough Endoplasmic Reticulum is studded with ribosomes, and is also the site of protein synthesis.
  • This type of ER is especially prominent in certain kinds of cells like hepatocytes where active protein synthesis occurs.
  • Proteins are produced for the plasma membrane, Golgi apparatus, secretory vesicles, plant vacuoles, lysosomes, endosomes and the endoplasmic reticulum itself.
  • It is in the rough ER for example that four polypeptide chains are brought together to form hemoglobin.

Current occupation

I am involved in protein production, protein folding, quality control and despatch.

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What is the difference between rough endoplasmic reticulum and smooth endoplasmic reticulum?

Rough endoplasmic reticulum, otherwise known as rough ER is considered rough because it is studded with ribosomes. Smooth endoplasmic reticulum has a more round tube-like shape. The purposes of the two are also different rough ER is used for building and folding proteins, whereas, smooth ER's job is associated with the production and metabolism of fats and steroid hormones.

Comparison