Is ICSI better than IVF?

Know the benefits of ICSI over IVF

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So patients who are thinking about having a test-tube baby always have one of the common queries that's what's IVF and what’s ICSI or intra-cytoplasmic sperm injection and what is the basic difference between them. Also which one is best because they are doing tons of research you can find online, then they get much confused about why they're going to have ICSI or why to opt for IVF or why they can not have both ,etc. So let's figure this out.


Now, what are the factors that affect the success of the ICSI?

As per Dr. Mukesh Mahajan who is one of the best general physician in Pune, the factors that affect ICSI are - the standard of the egg, quality of sperm, the expertise of the embryologist who is doing ICSI, and therefore the condition of the lab where the entire procedure takes place.


Dr. Nisarg Patel – a renowned gynecologist, stated below the explanations where ICSI is better compared to IVF. He also runs a clinic, namely Nisha IVF Clinic. It offers affordable treatment safely and most reliably & is one of the best IVF centre in Ahmedabad. The centre has the best & latest technology and a team of experts for a successful IVF treatment in and around Ahmedabad.


Let's see the explanations or conditions stated by Dr. Nisarg Patel, where ICSI is better than IVF are-

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• Now in IVF what happens once we collect the eggs from you we mix the eggs, and therefore the sperm in a Petri dish and the sperm fertilizes the egg on their own, and thus the natural fertilization process takes place. But just in case of ICSI, what happens is that we get the egg, then we slick the best available sperm, i.e. a mature motile sperm. If we get that or a light spot, then we inject the sperm into the egg then it gets fertilized so here the embryologist is selecting the sperm and is injecting that into the egg.


• Now why we choose ICSI, and that we can't do IVF in some instances. Therefore the indications of ICSI are if the amount of motels sperm is deficient meaning the probabilities of spontaneous fertilization of the egg with the sperm are low that’s once we choose ICSI or the morphology of the sperm isn't good. A low morphology sperm meaning the sperms are defective and it's not going to fertilize the egg.


• Also if there was a previous fertilization failure once you had an IVF before and none of the eggs fertilized when mixed with the sperm. So when we take the next chance, we usually choose ICSI because the probabilities of success in ICSI are far better than IVF though the pregnancy rate is almost the same.


In case once we opt for a surgically retrieve sperm meaning the man does not have the sperm and that we are getting the sperm after doing a little surgery like things ax or TZ flu. In that case, we extract sperm by making a little nick in the scrotum, then we retrieve that sperm.


• So once we have a minimal number of sperm or only a couple of sperm, therein case, we've to wait for a few weeks because the numbers of sperms are very less. Also if there's unexplained infertility like we do not know why the couple isn't getting pregnant while everything being normal. So in such cases to extend the prospect of fertilization we choose ICSI.


• If the sperm was frozen at an earlier date and once we call the sperm we see that very less or few sperms are in good condition, then in such cases we choose ICSI to avoid fertilization failure.


• If you would like to opt for genetic testing like pre-implantation genetic testing called PGD or PGS so in such a case, we've to opt for ICSI because if we choose IVF and there are very less or few sperms and here, then we do not get the best results. Hence, we choose single sperm fertilization and is a procedure of choice.


• In certain conditions like problems with sperm not able to penetrate the embryo or there are tons of anti-spam antibodies in such a case ICSI is often a far better option compared to IVF.


• Now if we compare two, IVF the fertilization occurs around 50 to 80 percent of the injected egg just in case of ICSI. Still, there are chances that the ICSI may damage the egg even if the procedure is done perfectly alright. The eggs might not fertilize, or maybe if the egg fertilized the embryo lives for a few days then the embryo gets dead, so in such a case, the ICSI procedure is more successful.


• We aren't getting a good quality embryo, so if we compare between IVF and ICSI, the fertilization rate of ICSI is more than IVF. Still, the pregnancy rate of IVF and ICSI is almost the same unless there's a gross malefactor abnormality.