Klinefelter Syndrome

Jill Pitelka


Klinefelter syndrome is a genetic disorder that only effects males. Men are supposed to have one X and one Y chromosome but instead are born with one or more extra X chromosome which causes them to have many different complications.


Children and adults have different symptoms.

Children symptoms: Children's symptoms tend to be different but some include, speech disabilities, sensitive, and being quiet and unassertive.

Adult symptoms: Young adults and adults tend to be taller than average, Klinefelter results in little body hair, enlarged breast, higher chance of getting breast cancer, wide hips, they get traits that are more usual in women. A lot of men are also not able to produce a child.

Can this be inherited?

Klinefelter syndrome cannot be inherited, instead happens random. It is caused by homologous cells not dividing properly in Meiosis resulting in the number of chromosomes in each cell not being correct.

Tests and treatments

Testosterone can be injected or taken by pill and it fixes the physical traits of Klinefelter. It builds a more overall masculine appearance by deepening the voice, improving muscle mass, and promoting hair growth. You can't be tested for Klinefelter Syndrome but you find out around the time of puberty when body hair, deeper voices, and muscles should be developing. But instead a man with Klinefelter will not undergo this.

Current research and studies

According to endocrinologist Adrian Dobs, if testosterone is started to be used at a younger age, it can prevent issues and properly develop bones and muscles.


"Klinefelter Syndrome." Genetics Home Reference. Service of the U.S. National
Lib. of Medicine, 28 Mar. 2016. Web. 5 Apr. 2016.

"Klinefelter Syndrome - Topic Overview." WebMD. WebMD, 2016. Web. 5 Apr. 2016.

"New Hope for Those with Klinefelter Syndrome." John Hopkins Medicine. John
Hopkins, 30 Sept. 2013. Web. 5 Apr. 2016.

"What Are the Treatments for Symptoms in Klinefelter Syndrome (KS)?" National

Institutes of Health. National Institutes of Health, 25 Oct. 2013. Web. 5
Apr. 2016. <https://www.nichd.nih.gov/health/topics/klinefelter/