Come to Party with Herpesviridae

Hang out with the large family of DNA viruses!

Here's What Goes on at the Party!

The viruses in the Herpesviridae family are all large viruses with a linear double-stranded DNA genome. They are enveloped viruses that can exhibit pleomorphism - shape and size may alter with every passing generation. One key trait of the family is the ability to infect the host with a latent infection and remain in host cells for the life of the host.

Herpesviridae Party in Human 300940

Friday, Dec. 11th, 9pm

301 Mount Airy-Harbourton Road

Lambertville, NJ

You can get here by being spread by direct contact or through bodily fluids, namely saliva.

Virus Life Cycle - The Party Never Ends!

Here's how it goes...

  1. The virus invades the cell by fusing its envelope with the cellular envelope.
  2. Once envelope fusion is completed, the viral tegument and capsid are transported to the nucleus of the infected cell using cytoskeletal proteins.
  3. The capsid injects the linear viral DNA into the nucleus.
  4. A product protein of the UL41 viral gene affects multiple cellular functions, including shutoff of host protein synthesis, degradation of host mRNA.
  5. Viral DNA is replicated and must be packaged into a new capsid.
  6. Once the capsid has left the nucleus, it must receive its tegument and secondary envelope.
  7. Virus begins the lytic cycle.
  8. Latency is achieved when the virus migrates in peripheral nuerons that innervate the epithelial cells where the infection is active.
  9. End of lytic cycle.
  10. Viral genes are deactivated during latency, to prevent the lytic cycle from activating in the neuron.


Once you come to the party, you never leave! We stay in this host until the day they die... unless they exchange body fluids with another host. In that case, some of us can explore a new body. Keep an eye out for any pesky drugs trying to ruin our fun.