Structural Brain Changes

For Caretakers of the Blind

Big image
"There is an estimated 180 million people worldwide who are visually disabled. Of these, between 40 and 45 million persons are blind and, by definition, cannot walk about unaided. They are usually in need of vocational and/or social support." (World Health Organization)

Blindness and the Developing Brain

Vision plays a large role in how we interact with the world around us. According to a journal article from Frontiers in Psychology, "the primacy of vision is structurally embedded in cortical organization as about one-third of the cortical surface in primates is involved in visual processes." (Kupers et al, 2011) The loss of vision definitely has an impact on brain organization and the way that an individual interacts with the world around them.

Scientists from the UCLA Department of Neurology have discovered that blindness causes structural changes in the brain. This indicates that that the brain might reorganize itself functionally in order to adapt to a loss in the sense of sight. (University of California-Los Angeles, 2009) Researchers found that the regions of the brain responsible for vision were smaller in blind individuals than sighted ones. However, in the blind, non-visual areas of the brain were found to be larger in the blind. Therefore, the other senses grow stronger. Researchers suggest that this is the result of blind individuals compensating for the areas usually used for vision. It appears that the brain compensates for the lack of sight and this is especially apparent in people who have been blind since birth. The brain has much more plasticity during this time, which allows much more development of the other senses.

Individuals who are blind have other ways of seeing our world, such as reading with braille. The following video presents the challenges of raising a child who is blind and presents the way that a child will learn to adapt to their lack of sight.

Early Intervention: Helping babies with visual impairments

How Did They Find It Out?

Using brain imaging, researchers examined individuals who have lost their sight at birth or before the age of five, people who have lost sight after 14 and individuals who still had their sight. They compared the groups and found that the loss and gain of brain matter depended on when the blindness originally occurred. (University of California-Los Angeles, 2009) In the group that was born blind or became blind before the age of 5, the brain showed difference from the other two groups in the corpus callosum, which is the area of the brain that transmits visual signals. It was found in both blind groups that they had enlargement in the areas not responsible for transmitting vision. The individuals without blindness that were tested did not show these enlargements in these areas of the brain.

In the following video, Professor Brian Wandell of Stanford University tells the story of Mike May, a world-record holding skier that is blind and how he adapted and became who he is today. The video also shows brain scans of blind individuals and sighted individuals, which shows the contrast of how the world is perceived through both groups. The video presents many of the same ideas presented above.

Understanding Blindness and the Brain (Brian Wandell, Stanford University)
Big image

These Brain Scans Show..

These brain scans come from a peer-reviewed journal article on the the nature of consciousness in the visually deprived brain.

"Anatomical and metabolic changes in the congenitally blind brain. (A) Axial brain slices showing reductions in gray (red) and white matter (blue) in congenitally blind compared to matched sighted control subjects. All components of the visual system in the blind are reduced in volume (after Ptito et al., 2008b). (B) Differences in cortical thickness between congenitally blind and sighted control subjects. Despite a reduction in volume of the occipital cortex, cortical thickness of the cuneus is increased in congenitally blind subjects (unpublished data from our lab). (C) Mid-sagittal brain slices showing increased resting-state glucose metabolism in the congenitally blind brain. Illustrative examples of cerebral glucose metabolism in a congenitally blind (left) and a normal sighted control (right) subject (Kupers et al., 2009)." (Kupers et al., 2011)


Kupers, R., Pietrini, P., Ricciardi, E., & Ptito, M. (2011). The Nature of Consciousness in the Visually Deprived Brain. Frontiers in Psychology Front. Psychology, 2. Retrieved from

World Health Organization. (n.d.). Blindness: Vision 2020 - The Global Initiative for the Elimination of Avoidable Blindness. Retrieved March 15, 2016, from

University of California-Los Angeles. (2009, November 19). Blindness causes structural brain changes, implying brain can re-organize itself to adapt. Retrieved March 15, 2016, from