Ebola Research

By: Areeba Shaikh

Symptoms

Symptoms start within 2-22 days.

Symptoms includes: The patient first starts with initial symptoms including fever, headache, joint and muscle pain, sore throat, rash, stomach pain, hiccups and difficulty breathing. Later, the patient may experience internal bleeding that results in vomiting or coughing blood.

Causes

Scientists say Ebola had been introduced to the human population through the blood, organs or other body fluids from infected animals. Some of these animals include bats, monkeys, gorillas, chimpanzees, and porcupines. You can also get the virus from other people who have the virus. The virus is most common in West Africa where there are many jungles with mammals and people who eat those mammals who often have the virus.

How is the immune cell involved in immune response?

When Ebola enters the body they first infect the Dendritic cells which are the "brain" of the immune system. Then, the virus tells the b cells (memory cells) to kill themselves and cause cells in the blood vessels to come out causing internal bleeding. When t cells (natural killers) try to attack the Ebola virus, they get infected by them causing the entire immune system to be defeated. The infected cells are later turned into factories that create billions of Ebola viruses that is likely to defeat the body.

How Ebola Viruses Replecates

Ebola Virus starts with the lysogenic cycle then ends with the lytic cycle.

  1. Attachment- The virus attaches to host cell

  2. Going in the cell- Ebola virus envelope and cellular membrane of the cell bond together and the virus gets released.

  3. Transcription- Virus DNA integrates into the host cell chromosomes, which is then translated into viral protein.

  4. RNA strand is synthesized to be used as a template strand to create a single strand RNA.

  5. When the host cell reproduces, it copies the viral DNA and is transmitted into the daughter cells. (cell division produces many infected cells with the infected DNA)

  6. The cells burst and release more viruses

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Treatment

There is no cure for Ebola. Treatment included an experimental serum that destroys infected cells. Doctors manage the symptoms of Ebola with fluids and electrolytes. Doctors can manage the symptoms with: Oxygen, blood transfusion, blood pressure medication, and fluids and electrolytes.

Prevention

You can prevent yourself from catching the Ebola Virus by doing each of the following:

  1. Avoid contact with infected people.

  2. Avoid areas that are having Ebola outbreaks. and

  3. Avoid contact with infected people’s blood and body fluids.

Photomicrographs of the Ebola Virus