Xao Tam Phan

Anti-Cancer Impact Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is really a Vietnamese traditionally medicinal plant used in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to investigate the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data show that the application of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.
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Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims with this study would determine the results of numerous drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The outcome established that microwave drying was a highly effective method in eliminating water with regards to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity from the P. trimera root while methanol and microwave-assisted extraction were the top solvent and means for greatest extraction from the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings from this study allow retaining the greatest degrees of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application within the nutraceutical industry.
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