A bad disorder
What is Werner syndrome?
Werner syndrome is characterized by the dramatic, rapid appearance of features associated with normal aging. affected individuals may develop disorders of aging early in life, such as cloudy lenses (cataracts) in both eyes, skin ulcers, type 2 diabetes, diminished fertility, severe hardening of the arteries (atherosclerosis), thinning of the bones (osteoporosis), and some types of cancer.
How common is Werner syndrome?
Werner syndrome is estimated to affect 1 in 200,000 individuals in the United States. - This syndrome occurs more often in Japan, affecting 1 in 20,000 to 1 in 40,000 people.
How do people inherit Werner syndrome?
Werner syndrome is inherited in an autosomal recessive pattern, which means both copies of the WRN gene in each cell have mutations. The parents of an individual with Werner syndrome each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.