Sickle Cell Disease

Or called (SCD)

Sickle Cell

There are lots of Genetic Disorders in the world. People you see daily my have a Genetic Disorder. Some Disorder are Tay-Sachs, Williams Syndrome, but the most common is called Sickle Cell. It is all over the world.

RESEARCH

What is the disease? What does the disease do to person?

Sickle cell disease is a blood disorder that's effect red bloods cells shape from a circle to a sickle shape. Sickle cell have blood that contain hemoglobin. It affects the red blood cells causing episodes of sickling with produce pain.

How many people are affected? Who is affected? How common is it?

In the USA about 100,000 people about 1000 babies are born with sickle cell and three millon people have the trait. In Africa main Nigra 90,000 people have SCD. The people that are main affected is African Americans and it is main in kids. Sickle cell is the most common Disorder it is found in Africa, American, Sub Saharan, and it is in every other country.

What causes it?

Sickle Cell is cause by a genetic mutation in genes that tell your body to make hemoglobin.

How is it inherited?

Sickle cell anemia is inherited as an autosomal recessive condition. This means that the gene can be passed on from a parent carrying it to male and female children. In order for sickle cell anemia to occur, a sickle cell gene must be inherited from both the mother and the father, so that the child has two sickle cell genes.

How is it diagnosed? Can you test or screen for it?

Sickle cell anemia is diagnosed with a simple blood test. Early diagnosis of SCD is very important. In the United States, a sickle cell anemia test is required as part of all newborn screening programs. If this test detects sickle hemoglobin in the blood, a second blood test is performed as soon as possible. You can test and screen test for SCD.

What are its symptoms?

SCD stop oxygen from going to the spleen, liver,lungs other organs. Often, the first sign of SCD is pain or swelling in the child’s hands or feet when small blood vessels become blocked. This causes some children to develop a fever.

How is the disease/ Disorder treated?

Most pain related to SCD can be treated with over the counter pain medications such as ibuprofen and aspirin. Some people who have severe pain are given opioid medications daily, along with additional pain medication. Some people may be admitted to the hospital for intense treatment. Other treatments are bone morrow transplant or blood transfusions.

3 interesting things about SCD!

1)One in every ten African-Americans has sickle cell trait, and one in five-hundred has sickle cell disease.

2)There is still no universal cure for sickle cell disease.


3)On the 15th of November 1910, Dr. James Herrick made the first official description in published literature of sickle cell disease. The cardiologist had a young patient, Walter Clement Noel, from the Caribbean island of Grenada with the disease under his care. He displayed symptoms of what we now refer to as acute chest syndrome, a common complication of sickle cell disease.