Gram-Negative Infections

By: Melai Evans

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"Gram-negative bacteria cause infections including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis in healthcare settings. Gram-negative bacteria are resistant to multiple drugs and are increasingly resistant to most available antibiotics. These bacteria have built-in abilities to find new ways to be resistant and can pass along genetic materials that allow other bacteria to become drug-resistant as well. CDC’s aggressive recommendations, if implemented, can prevent the spread of gram-negatives." Information from the CDC


In some cases, bacteria can enter the body through urinary and intravenous catheters, ventilators, or wounds. Open wounds are the most common. These types of infections affect the very ill and the elderly and are often difficult to treat. This is why it is important to keep wounds cleaned.


It is diagnosed by the symptoms like...

  • confusion
  • high fever
  • lack of interest in eating or drinking
  • nausea
  • seizures
  • sensitivity to light
  • severe headache
  • sleepiness
  • stiff neck
  • vomiting


The frequency is less then 10% a year.


It is resistant to most antibiotics. The only thing that doctors can really use are drugs such as colistin, which can have toxic side effects.