The Rabies Virus
Symptoms
Symptoms
- Fever
- Headache
- Excess salivation
- Muscle spasms
- Paralysis
- Mental confusion.
Structure of the virus
The Rabie Virus is approximately 180 nm long and 75 nm wide. The rabies genome encodes five proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G) and polymerase (L). All rhabdoviruses have two major structural components: a helical ribonucleoprotein core (RNP) and a surrounding envelope. In the RNP, genomic RNA is tightly encased by the nucleoprotein. Two other viral proteins, the phospoprotein and the large protein (L-protein or polymerase) are associated with the RNP.
The cross-sectional diagram demonstrates the concentric layers: envelope membrane bilayer, M protein, and tightly coiled encased genomic RNA.
Host
Replication
Injury Claim
Pain areas: in the muscles
Whole body: dizziness, fatigue, fever, loss of appetite, or malaise
Psychological: delirium, fear, or hallucination
Gastrointestinal: nausea or vomiting
Muscular: muscle spasms or paralysis with weak muscles
Behavioral: aggression or irritability
Treatment and Prevention
Treatment --- The most common treatment of rabies is with postexposure prophylaxis The first step in treating rabies and to reduce the likelihood of developing symptoms is to wash the wound with soap and water