Hexa gene mutation disorder affecting children.
Children will start having speech problems and loss of motor skills. They can develop muscle weakness. They will also have slower development compared to other kids. They also could have seizures and diminishing mental function. Most children do not live past the age of 4 years olds.
Chromosome 15 and the hexa gene are affected. This disrupts the activity of beta- hexosaminidase which affects the brain and spinal cord.
There is no cure. Possible treatments include bone marrow transplant, gene therapy, anticonvulsant medicine.
- Each child has 25% chance of having this disease if both parents are carriers.
- Tay-Sachs is most common in Eastern European Ashkenazi Jews.
- A blood test can determine if you carry or have the disease.