U.S. FDA Has Approved SOVALDI - Available Online In India

The United States Food and Drug Administration has approved Sovaldi 400 mg tablets for treating chronic hepatitis C infections. It is used together with other antiviral medicines to achieve this goal. This medicine is also known as Sofosbuvir and it should be taken once daily. It is a nucleotide analog inhibitor of the HCV NS5B polymerase enzyme. This enzyme plays an important role in the replication of the hepatitis C Virus (HCV).

Sofosbuvir is a direct acting agent. This means that it interferes directly with the life cycle of HCV by suppressing viral replication. The efficiency of Sovaldi has been established in patients with hepatitis C virus genotypes 1, 2, 3 and 4 or infection. This includes those with hepatocellular carcinoma and awaiting liver transplantation and those with a HCV/HIV-1 co-infection.

Hepatitis C is a viral ailment which causes inflammation of the liver, leading to liver failure or diminished liver function. Most people infected with hepatitis C do not display symptoms of the ailment until liver damage becomes apparent. This can take a number of years. Some people with chronic hepatitis C virus infection develop poor liver function or cirrhosis over many years, leading to complications like jaundice, bleeding, liver cancer and accumulation of fluid in the abdomen. Sofosbuvir has demonstrated efficacy and safety when it comes to treating various kinds of HCV infection without the need to co-administer interferon.

The recommended treatment duration and regimen for Sofobvir combination therapy in HCV/HIV-1 con-infected or HCV mono infected patients is as follows:

Genotype one or four

Treatment: Sovaldi + ribavirin + Peg-interferon

Duration: 12weeks

Genotype two

Treatment: Sovaldi + ribavirin

Duaration: 12 weeks

Genotype three

Treatment: Sovaldi + ribavirin

Duration: 24weeks

The treatment regimen, duration and response to Sofosbuvir are dependent on patient population, viral genotype and associated baseline factors. Sovaldi has some side effects. The most common side effects associated with the use of Sovaldi + ribavirin + peginterferon alfa are nausea, fatigue, anemia, headache and insomnia. The common side effects associated with the use of Sovaldi + ribavirin are headache and fatigue. If you experience these side effects while taking this medication, it is wise to consult your physician promptly.

It is not recommended to take Sovaldi together with other medicines like rifampoin, St John’s Wort, Phenobarbital, oxcarbazepine, carbamazepine, rifapentine, rifabutin, phenytoin, and tipranavir. Such coadministration can reduce the concentration of Sovaldi, affecting its therapeutic effect. Sofosbuvir combination treatment with peginterferon alfa + ribavirin or with ribavirin is not recommended in expectant women or those who plan to conceive due to the risk of fetal death or birth defects associated with ribavirin.

Sovaldi is available online in India.One of the firms that distribute this prescription medication in India is ACT Life Sciences. You can purchase Sofosbuvir online from the website of ACT Life Sciences and it will be delivered to the address you specify within five to seven days. Since Sovaldi is a prescription drug, you need to have a valid medical prescription that is issued by a registered oncologist when placing your order. Once ACT receives the prescription, it will confirm your order and ship the drug.

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