Lou Gehrig's Disease (A L S)

Biology Research Project

Why? Lou Gehrig's Disease

I chose Lou Gehrig's Disease because I have saw all these (ALS) ice bucket challenges and i didn't know what they were for. So when I heard that it was for a disease I wanted to find out more about Lou Gehrig's Disease.

Lou Gehrig's Disease, A progressive neurodegenrative disease that effects nerve cells in the brain/ spinal chord. The body gained weakness in muscles. Their bodes eventually become paralyzed. Mainly effects arms and legs.

Symptoms And Body Parts

The main body parts is their Arms, Legs.

Symptoms - muscles quiver and weakness in them. Also common symptoms termer, lack of restraint, drooling, paralysis, cramping, apathy, fatigue, unintentional weight loss, difficulty swallowing

Causes of (A L S)

Although the cause of ALS is unknown, heredity plays a role in 5% to 10% of cases. A fraction of all cases of familial ALS (that is, inherited ALS) is believed to be caused by a defective gene that prevents the body from producing a normal amount of an enzyme called superoxide dismutase. This enzyme helps neutralize free radicals -- highly reactive oxygen molecules produced during metabolism and capable of damaging body tissues.
Lou Gehrig's Disease - Effects of Lou Gehrig's Disease - What Is ALS Video.mp4

Inherited By

About 90 to 95 percent of ALS diagnoses are not inherited. An estimated 5 to 10 percent of ALS is familial and caused by mutations in one of several genes.
Caley and Greg ALS Story

Age Group, Location, And Is The Disease Common

Most people who develop ALS are between the ages of 40 and 70 years old. Some cases of the disease do occur in persons in their 20 and 30. Generally though, ALS occurs in greater percentages as men and women grow older.

ALS it is known that military veterans, particularly those deployed during the Gulf War, are approximately twice as likely to develop ALS. ALS is more likely to be impact on them because of their environmental and/or lifestyle factors. People are unclear of why it has an effect on them.

Genes That Cause ALS

Mutations in this gene account for between 25% and 40% of all familial ALS cases (depending on the population), and also approximately 4% to 6% of sporadic cases. As noted above, these apparently sporadic cases are in fact genetic. The gene mutation appears to act in a dominant manner.


No cure has yet been found for ALS. But there are various drugs to help keep symptoms and living with disease easier. Rilutek is an approved drug for (ALS). How it works is not exactly known, but it seems to prevent the damage that can result from the nerve cell being overexcited by glutamate. May improve functioning and survival. Because of potential side effects involving the liver, close monitoring by your doctor is required.

Physical therapy can improve circulation and help prolong muscle use in the early stages of ALS. In addition, various medications may be prescribed as the disease progresses to help with symptoms.

Lou Gehrig's Disease Diagnosed

- Blood Work

- Cerebrospinal Fluid Examination

- Electromyogram

- Genetic Test

Mainly Doctor's can tell when there patient has this disease. Because they can tell by the way they are acting and the symptoms.

What I Learned

Everything that y'all have seen on this page is what I have learned. I choose this because I didn't know anything about this disease. My heart goes out to every single person that has Lou Gehrig's disease. Because I have learned so much about these people and their disorder. It breaks my heart to see how these people suffer day by day in their life's. The people that have (ALS) have to be really strong to deal with this disease, (their fighters). I pray for them, that God gives them strength to make it day by day. This is definitely something I would love to work in. By helping them live day by day not knowing whats going to happen at the end of each day. I love every single person that has this disease most of them are sweet but they have there good days and Bad ones. I have Faith that one day they will find a cure for Lou Gehrig's Disease.