By: Stanley Joseph

Smallpox in the New World

Smallpox was brought into the New World by the Europeans. This disease killed about 90% of the entire native population of the New World. The first smallpox epidemic occurred in 1518, and it spread through all of Mexico and through South America. The crazy outbreak killed almost a third of their population in just a few months.

Native Americans and Smallpox

The Native Americans had no prior exposure to Smallpox, so this made them even more susceptible to the disease. The Native Americans were isolated before the Europeans came, so their immune systems were not ready to take on Smallpox.