Sickle Cell Anemia

Human Heredity Project By: Mariah White

What is Sickle Cell Anemia?

  • Sickle Cell Anemia is also know as HbS disease or SCD.
  • It is an heredity disorder that has a mutation on the gene that effects your body's production of hemoglobin.
  • The recessive disorder is on chromosome 11.
  • The name is because of the way the effected blood cell takes shape, it looks similar to a sickle.

How can this be diagnosed?

  • If doctors suspect that there is a greater chance of a baby having Sickle cell they can do prenatal testing using amniocentesis.
  • Some of the symptoms are infections, pain, and fatigue.
  • This effects 70,000-100,000 Americans.
  • It mostly effects people of African descent.

What happens to a child that has Sickle Cell Aniemia?

  • It can last for several years or your lifetime.
  • People effected with Sickle Cell Anemia have a higher chance of death earlier, like in their 50's, caused by organ failure with is a result of the Sickle Cell.
  • Someone with Sickle Cell can have children, but there is a chance that they will be effects based on what type of Sickle Cell a person has and if the other parent would have the disease.

What research is being done to help cure Sickle Cell Anemia?

  • The only cure for Sickle Cell is a bone marrow or stem cell transplant. Of course you would have to find a donor that is a close match to you, it may not work, and there are serious side-effects including death. Because if this it is only for people with severe sickle cell anemia and minimal organ damage.
  • Some ways to manage Sickle Cell Disease are: taking folic acid supplements regulatory, blood transfusions, and pain medications.
  • in 2010, scientists found that Sickle Cell Anemia and brain function may be related.