Hodgkin’s Disease

General Information, Symptoms, and helpful resources

General Information

-Synonyms of Hodgkin’s Disease

  • Hodgkin's Lymphoma
  • Hodgkin Disease


Hodgkin Disease is a type of cancer known as lymphoma. Hodgkin's Lymphoma affects that lymphatic system, specifically the lymphatic system. Often, tumors will form within the lymph nodes or the surrounding area. The cause of Hodgkin Disease is unknown

-Signs of the disease.

  • Swollen lymph nodes (usually around the neck area)
  • The spread of swelling to other lymph nodes

-Symptoms of the disease.

  • Swollen lymph nodes (usually around the neck area)
  • The spread of swelling to other lymph nodes


  • The exact cause of the disease is unknown. However, early research suggests that a virus may play a role in contracting the disease. Also, genetic susceptibility may give an individual a higher chance of getting the illness.

-Affected populations

  • Majority of individuals with the disease are between 15 and 40.
  • As the age increases, the chance of contracting the disease decreases.
  • The four types are: nodular sclerosis, mixed cellularity, lymphocyte predominant, and lymphocyte depleted.

-Related Diagnosis

  • Burkitt’s lymphoma is a lymphatic system cancer that affects the lymph nodes as well as other areas of the body.
  • Non-Hodgkin’s lymphomas are a group of cancers of the lymphatic system.
  • The presenting symptoms of Hodgkin’s disease may mimic many infectious diseases.


The diagnosis of Hodgkin’s Disease is suspected, determined by clinical evaluations, patient history, and symptoms. A diagnosis by the removal of tissue is also a possibility. The tissue is studied to see if Reed-Sternberg cells are present.

Standard Therapies

The main two main therapies of Hodgkin's Disease include Radiotherapy and Chemotherapy. The Radiotherapy destroys lymphocytes and helps to shrink the enlarged lymph noes while chemotherapy uses anticancer drugs.

Supporting Organizations


Morrison C, et al., Hodgkin’s disease in primary care. Nurse Pract. 2000;25:44, 47-50, 56.

Johnston LJ, et al., Autologous hematopoietic cell transplantation in Hodgkin’s disease. Biol Blood Marrow Transplant. 2000;6:289-300.

Santoro A, et al., Gemcitabine in the treatment of refractory Hodgkin’s disease: results of a multicenter phase II study. J Clin Oncol. 2000;18:2615-9.

Scully RE, et al., Case records of the Massachusetts General Hospital. N Engl J Med. 1997;337:1753-61.

Mack TM, et al., Concordance for Hodgkin’s disease in identical twins suggesting genetic susceptibility to the young adult form of the disease. N Engl J Med. 1995;332:413-8.

Diehl V, et al., Hodgkin’s disease-environmental or genetic? N Engl J Med. 1995;332:463-4.

Bonadonna G, Treatment strategies for Hodgkin’s disease. Semin Hematol. 1988;25:51-7.

American Cancer Society Logo. (n.d.). Retrieved December 2, 2015, from https://en.wikipedia.org/wiki/File:American_Cancer_Society_Logo.svg