Hypertrophic Cardiomyopathy

Megan,Kavi,Ryan

Pathophysiology

Inflammation, Cell Damage, Hyperplasia, Dysplasia, Necrosis

Symptoms

Atrial Fibrillation

Orthopnea

Dyspnea on exertion

Syncope

Angina

Fatigue

Edema

Tachypnea

Joint Pain

Abdominal Pain

Tests and diagnosis

Echocardiography shows left ventricular hypertrophy and a thick, asymmetrical intraventricular septum disrupting flow in ventricles.

Cardiac catheterization reveals elevated left ventricular enddiastolic pressure.

Chest x-ray may show significant of moderate increase in heart size.

Thallium scan usually reveals myocardial perfusion defects.

Treatment and Prognosis

Drug therapy is generally the most common treatment. Beta-adrenergic blocking agents are used to slow the heart rate and increase ventricular filling by relaxing the obstructing muscle. Calcium channel blockers may also reduce elevated diastolic pressures and increase exercise tolerance. Surgery is performed rarely and only when all else fails

History and Research

It was first discovered in 1989, and since then most of the genes of the proteins responsible for the formation of muscle tissue have been found. It is generally carried down genetically.

Risk Factors

-Family

(50% of the time Hypertrophic Cardiomyopathy is transmitted genetically)

-Aging

-Diabetes

-Elevated sugar, fats, and protein in blood

-hypertension

-Obesity

-Inactive lifestyle

-Smoking

-Stress

-Drug Use (amphetamines or cocaine)

Famous Sufferers

-British comedy actor Leonard Rossiter (dead)

-Marc-Vivien Foé and Miklós "Miki" Fehér (Soccer players dead)

-Corey Haim (Actor, dead)

- Many NFL and baseball players

Support Groups

-The Cardiomyopathy Association (http://www.cardiomyopathy.org)

-www.supportgroups.com (you can go there are talk about your problems and other people can see what you write and respond)

Stanford Hospitals and Clinics: FAQ: hypertrophic cardiomyopathy and implantable defibrillator