Leukemia

Hodges, Qu'Ran Y.

Leukemia

In 1827 Leukemia was first recognized by the anatomist and surgeon Alfred-Armand-Louis-Marie Valpeau. In 1847 Rudolf Virchow gave more descriptive information about Leukemia after examining the bone marrow of a patient with Leukemia. Virchow called the genetic disorder Leukämie in German. He composed the name from two Greek words (leukos and haima) meaning "white" and "blood". He also recognized Leukemia not as a genetic disorder but a family of them containing many variations of Leukemia.
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Type of Genetic Disorder

Leukemia is a family of cancerous genetic disorders. Leukemia occurs when an abnormality occurs in chromosome 22 known as the Philadelphia translocation. The Philadelphia translocation makes the 22nd chromosome unusually short because of reciprical translocation of the genetic material between chromosome 9 and 22. Which causes certain proteins to always signal cells to grow large and divide uncontrollably. Unlike other cancers Leukemia may not always produce a mass known as a tumor.

Symptoms / Effects of Leukemia

Symptoms and Effects of Leukemia may but are not limited to:

- Signs of Internal Bleeding (easily being bruised)

- Loss of appetite and/or unexplained substantial weight loss

- Fatigue

- Swelling and/or pain on left side of abdomen

- Loss of Hair

- Immune system worsens

- Swollen lymph glands

- Anemia

Diagnosis

Physical Exam

Leukemia is first diagnosed by a physical exam this a conversation with the patient which would give information about his or hers sleeping and eating habits. And also if they had experienced any joint pain.


Blood Test

After the physical exam has been conducted blood test are conducted to examine the normality of level of white blood cells and platelets.


Bone Marrow Test

Bone marrow is taken from the hip bone during a procedure using a Jamshidi needle to perform the hip biopsy. The marrow is then examined for Leukemia cells.

Leukemia diagnosis

Prognosis

Leukemia has a 24% five year survival rate. The survival rate of course depends on if the diagnosis of Leukemia is acute of chronic. Chronic forms of Leukemia are harsher than acute. A person who struggles with Leukemia slowly deteriorates as time passes. They become weak mentally and physically in most typical situations. Watching a loved one slip away to a seemingly uncontrollable and unforgiving disease is in the least for lack of a better word complicated.
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Treatments

Treatments for Leukemia include:


Stem Cell Transplation - When the cancerous cells are gone or weak a stem cell transplant can be used to replacedamaged bone marrow and promote healthy bone marrow growth


Chemotherapy - A set dosage of medicine that target and set out to destroy cancer cells though it can also kill healthy cells in the body


Radiation - Radiation is used to drop the number of white blood cells although radiation does not prevent the growth of new cancerous cells


Immunotherapy - Immunotherapy stops the growth of new cancerous cells though it does not kill existing cancerous cells

Current Research

Leukemia and Lymphoma Society

The Leukemia and Lymphona Society is a non-profit organization that researches and cancers that take place in the blood. They help raise resources to treat children and adults with Leukemia and Lymphoma, and also fund the research of new treatments.

Cancer Treatment Centers of America

The Cancer Treatment Centers of America is a leading organization of treatment and research of multiple types of cancer.

Bethany

After seeing her physician for bruising on her legs some extensive blood work was recommended. After a bone marrow test it was confirmed that she had chronic myloid leukemia (CML). She was able two have twins and is now in remission. Now Bethany is back at the forefront of running her company Gigi's Cupcakes.