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Chordopoxvirinae Orthopoxvirus aka Smallpox

Information About Smallpox

The last known case of smallpox in the U.S was in 1949, and the last known case in the world was in 1977. There is only one form of treatment and that is the smallpox vaccine. Vaccination 4-7 days after exposure may offer some protection from the disease and may lessen its severity. It can be a very lethal disease. The shape of the virus is a "brick-shaped" spherical


If someone does get smallpox, a doctor can recognize the disease because it causes a special kind of rash . The rash shows up as blisters on the skin that fill with fluid and crust over.

Also: high fever, chills, malaise, headache, severe back pain, abdominal pain, vomiting.

The last known case of smallpox's in the U.S was in 1949 and the last known case was in 1977.

How is it transmitted?

  1. Generally, direct and fairly prolonged face-to-face contact is required to spread smallpox from one person to another. Smallpox also can be spread through direct contact with infected bodily fluids or contaminated objects such as bedding or clothing.

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Edward Jenner and smallpox