By: Cole Krauter
Causes of Ebola
Ebola enters the body and first infects the dendritic cells which are the brain of the immune system. Then they tell b cells to kill themselves and cause cells in blood vessels to come out causing a lot of internal bleeding. When t cells try to attack they get infected by the virus causing your whole immune system to be defeated. The infected cells are turned into factories that create billions of Ebola virus.
Attachment- The virus attaches to host cell using a glycoprotein called peplomer on the viral envelope.
Going in the cell- Ebola virus envelope and cellular membrane of the cell bond together and the virus gets released.
Transcription- Virus uncoats and the nucleocapsid is transcribed into mRNA, which is then translated into viral proteins.
Glycosylation- The viral proteins are attached to glycans (saccharides). The glycoproteins are split into glycoprotein 1
RNA strand is synthesized to be used as a template strand to create a single strand RNA.
Heterodimers are multiplied to form trimers that will soon form into surface peplomers (glycoprotein spike on a viral capsid) for the new Ebola cells.
Viral RNA copies are made and trimers began to get out of the cell membrane.
Viral Envelope and nucleocapsids began to form and new genome prepare for budding
New Ebola viruses get released from the host cell, gaining the cell membrane.
Avoid contact with infected people.
Avoid areas that are having Ebola outbreaks.
Avoid contact with infected people’s blood and body fluids.