"Small, but powerful"
What is it?
Morquio Syndrome is a rare inherited birth defect. In children with Morquio syndrome, the body cannot break down sugar chains called glycosaminoglycans that help build bone, cartilage, eye corneas, skin and connective tissue. There are two types of Morquio syndrome: Type A - which an enzyme called galactosamine-6-sulfate is missing. Type B - in which there isn’t enough of the enzyme beta-galactosidase. It’s also a progressive disease, meaning symptoms get worse as the child grows. Some of the symptoms for Morquio syndrome are: Abnormal bones, spine development, bell-shaped chest, widely spaced teeth, possible heart and visions problems, knock knees, flat bridged nose. Those are just a couple out of the many there are. Morquio syndrome sometimes starts showing at birth as leg deformities, joint conditions, narrow chest, and skeletal dysplasia. If it does not show up at birth right away, it will progress as the child gets older and if it is not caught right away there is a great chance of death. Morquio syndrome is an autosomal recessive trait, which means both parents must carry the gene that causes Morquio for a child to have the disorder. If both parents carry a non working copy of a gene related to this condition, each of their children have a 25% chance of developing this disease. This syndrome is treated in many ways. The condition can affect several body systems, so there are different treatments such as: non-surgical or surgical treatments, and monitoring. Is it estimated to occur in every 1 out of 200,000 births.
Sarah Van Orden's story
Sarah Van Orden
This is her at 16 years old.
This is a knock knees. Sarah had to have 4 surgeries to get rid of these.
This is type A morquio syndrome.
If you have type A morquio syndrome, your back is crooked.
A cure for the incurable.
"Morquio Syndrome: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 04 May 2016.
"Morquio Syndrome." N.p., n.d. Web."MORQUIOSITY." MORQUIOSITY. N.p., n.d. Web. 04 May 2016.