Makkah is important to Islam because it is the spiritual center of Islam. It is also important to Islam because of the Kaaba. As stated above, Muslims direct their prayers to the Kaaba and religion is very important to Muslims, which makes this place important to Islam.
Makkah is also the birthplace of the prophet Muhammad. Muhammad's life was pretty tough growing up. His father died before his birth and his mother sent him to live with a nomad family in the desert. When he returned when he was five or six years old, his mother died. He then lived with his grandfather and then his uncle. Also, Muhammad was very poor. Around 610 CE he went to a cave in a mountain to pray and received a call to be a prophet (a messenger of God) from angel Gabriel. From then on, he taught people about treating other people with compassion, honesty and justice. He received messages from God through angel Gabriel for the next 22 years.