Ulcerative Colitis

By: Shelby Dampac and Abbey Hallman


Ulcerative colitis is an immune-mediated inflammatory disease. It is when there is inflammation in the large intestine due to a long lasting and abnormal response by the immune system. This disease only affects the colon and rectum with characterized by ulcers and open sores. The inflammation of the large intestine can cause painful and unpredictable symptoms that can vary for each person.

The main symptoms are:

* Stomach pain or cramps

* Diarrhea

* Bleeding from the rectum

* Fever

In addition, some individuals willhave loss of appetite and weight. Several cases shown that a person can have diarrhea 10-20 times in a day. Furthermore, ulcerative colitis can lead to more problems such as joint pain, liver disease, or eye problems.

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Many scientists do not know the real cause of ulcerative colitis. It was thought to be caused by stress or diet, however they know that there are several factors that could potentially trigger the disorder.


  • Environment: Foreign substances could have cause inflammation in the colon.
  • The Immune System: The abnormal immune system attacking cells in the digestive system.
  • Heredity: Ulcerative Colitis is more common with individuals who had this disease in their genes, but most of the time people who have ulcerative colitis do not have any evidence of this disorder in their family history


The treatment for ulcerative colitis depends on the severity of the disease which simply can be a combination of medications and changes in the diet. Medication such as antidiarrheal, suppositories, steroids, and aminosalicylates are usually used for any mild symptoms.

However, some cases with those individuals with severe and long-lasting pain might need more doses of medication or possibly surgery. Doctors might recommend use biologic products that will decrease the inflammatory response in the colon.

The treatment is most beneficial with the use of Aloe mucilaginous polysaccharides (AMP) which are long chain molecules made out of mannose and glucose molecules which has an anti-inflammatory effect in the gastrointestinal tract. AMP is found in the Aloe plant.