Mitochondrial Diseases

Adeline Flores, Chet Peterson, Taylor Ross

Description of Mitochondrial Disease

Mitochondria is responsible for creating more than 90% of energy needed for the body to keep growing and sustain life

Mitochondrial Diseases result from the failure of the mitochondria

Mitochondria is present in every cell except red blood cells

Mitochondrial Disease primarily affects children, but the disease in adults is becoming more common

Mitochondrial Disease causes the most damage to the cells in the brain, liver, skeletal muscles, kidney, the endocrine system and respiratory system

Types, Causes, Symptoms, and Other Potential Cures

Types of Mitochondrial Diseases

Alpers Disease

Complex 1 Deficiency

Complex 2 Deficiency

Complex 3 Deficiency

Complex 4 Deficiency/COX Deficiency

Complex 5 Deficiency

Leigh Disease/Syndrome

Luft Disease

Mitochondrial Cytopathy

Mitochondrial Myopathy
Pearson Syndrome

Respiratory Chain

Causes of Mitochondrial Diseases

Causes of mitochondrial diseases are genetic deficiencies, and long term nutritional loss. Once genes have been passed, it builds our bodies with traits carried from our parents along with any deficiencies and mutations. This means that the gene can go along the line from one person to another but can affect each person a different way. They are not caused by anything a person does and it is not contagious.

Symptoms of Mitochondrial Diseases

There are many symptoms an undiagnosed patient can experience. Some of the most common symptoms are; hearing loss, muscle weakness, cramping, and pain, seizures, trouble with coordination and balance, exercise intolerance, and learning deficits. This is because nerves and muscles cells have a high need of energy, but due to the fact that cells are lacking mitochondria, leads to complications such as these along with other heart, liver, and internal problems and malfunctions.

Recent Research for Potential Cures of Mitochondrial Disease

  • There are no recent potential cures for Mitochondrial Diseases.
  • You can take vitamins and supplements
  • If the disease affects motor skills physical therapy can be taken
  • Treatments can be tailored to meet the patient’s needs
  • Treatments may be effective enough to delay or stop the progression of the disease
  • Effectiveness of the treatment can vary, depending on the severity of the disorder

Careers in Regards to Mitochondrial Diseases

Doctors, Pediatricians, Neurologists, Geneticist, Medical Directors, Gerontologists, Anesthesiologist.

Living with a Mitochondrial Disease

Paralympian Joe Wise

How can we support someone who is/has been impacted by mitochondrial diseases?

You can help by donating to the United Mitochondrial Disease Foundation which promotes research and education for the diagnosis, treatment, and cure of mitochondrial disorders and to provide support to affected individuals and families.