Hemophilia

Shane Trovalli

What is Hemophilia?

  • Present in 1 out of every 5,000 male births in the United States of America
  • Hemophilia lowers blood plasma clotting factor levels of the coagulation factors needed for a normal clotting process. Thus when a blood vessel is injured, a temporary scab does form, but the missing coagulation factors prevent fibrin formation.
  • This is very dangerous, as it makes the smallest cuts bleed profusely and must be dealt with as extreme problems.


Life Expectancy is 10 years less than the average male.

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Symptoms

  • Hemarthrosis (bleeding into the joints) is characteristic of hemophilia. The knees and ankles are most often affected. The bleeding causes distension of the joint spaces, significant pain, and over time, can be disfiguring. Over time, joint destruction occurs, and joint replacement surgeries can be required.

  • Bleeding into the muscles may occur with hematoma formation (compartment syndrome).

  • Bleeding from the mouth or nose bleeds may occur. Bleeding after dental procedures is common, and oozing of blood from the gums may occur in young children when new teeth are erupting.

  • Bleeding from the gastrointestinal tract can lead to blood in the stool.

  • Bleeding from the urinary tract can lead to blood in the urine (hematuria).

  • Intracranial hemorrhage (bleeding into the brain or skull) can lead to symptoms such as nausea, vomiting, and/or lethargy.

Increased bleeding after surgery or trauma is characteristic of hemophilia.