Dwarfism

By Davide Caramellino

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Achondroplasia

Achondroplasia is a common cause of dwarfism. It occurs as a sporadic mutation in approximately 80% of cases (associated with advanced paternal age) or may be inherited as an autosomal dominant genetic disorder.

People with achondroplasia have short stature, with an average adult height of 131 centimeters (4 feet 4 inches) for males and 123 centimeters (4 feet 0 inches) for females. Achondroplastic adults are known to be as short as 62.8 cm (2 ft 0.7 in). The disorder itself is caused by a change in the gene for fibroblast growth factor receptor 3 (FGFR3), which causes an abnormality of cartilage formation. If both parents of a child have achondroplasia, and both parents pass on the mutant gene, then it is very unlikely that the homozygous child will live past a few months of its life. The prevalence is approximately 1 in 28,000,000.

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Dwarfism

Dwarfism is normally diagnosed when some one is less then 147 cm or 4ft 10 in. Dwarfism is a genetic mutation that you reserve from your parents, unfortunately because it is genetic there are no treatment.

Dwarfism can be diagnosed before birth by the use of prenatal ultrasound. A DNA test can be performed before birth to detect homozygosity, where two copies of the mutant gene are inherited, a lethal condition leading to stillbirths. But homozygosity is the only dangerous form of dwarfism, if only one gene is received it is not lethal.

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Also

if you ever encounter someone with dwarfism they prefer the name little people not midgets.