By: Kevin Danner
Progeria is caused through a genetic mutation that is located on chromosome 1. It is caused by a mutation in an autosomal dominant fashion. This means that it can be caused by a parent that has a non working gene. Even though it can be inherited through an autosomal dominant fashion, anyone can inherit progeria because it is a mutation and can randomly occur on chromosome 1. A parent that has progeria has a 50% chance of passing it on to their offspring.
Progeria is a very hard disease for scientists to cure, they have some clues as to how to cure it but there are no substantial leads. There was a drug that was originally used to treat cancer that has been used in experiments to try and treat progeria, but there has been little impact. Some scientists are also experimenting with growth hormones but there has been little success and as of now progeria is still incurable.
There are several symptoms that indicate a carrier of progeria. Some of the more noticeable symptoms include loss of hair, little weight gain, abnormal joints, protruding face features, and an appearance of aged skin. One of the more fatal symptoms is arteriosclerosis which hardens the arteries and can cause heart attacks and strokes. However, patients suffering from progeria are still able to do basic activities such as walking, sitting, and standing.
Tests and Treatments
Diseases and Disorders. Gale Virtual Reference Library. Web. 5 Apr. 2016.
Gulli, Laith Farid. "Progeria Syndrome." The Gale Encyclopedia of Genetic
Disorders. Gale Virtual Reference Library. Web. 5 Apr. 2016.
"Hutchinson-Gilford Progeria Syndrome." U.S National Library of Medicine.
Genetics Home Reference. Web. 5 Apr. 2016. <https://ghr.nlm.nih.gov/