What is it?
What causes Progeria?
90% of affected children have a mutation on the gene that encodes Lamin A, a protein that holds the nucleus of the cell together. It is believed that the defective Lamin A protein makes the nucleus unstable. This instability seems to lead to the process of premature aging among Progeria Patients. Progeria seems to occur without cause - it is not seen in siblings of affected children. The disease is not believed to hereditary.