Huntington's Disease

By: Connor Crosby and Jimena Razo


Huntington's disease is an inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain.

Symptoms of HD

amnesia, delusion, lack of concentration, mental confusion, slowness in activity and thought, or difficulty thinking and understanding

abnormality walking, increased muscle activity, involuntary movements, problems with coordination, loss of muscle, or muscle spasms

compulsive behavior, fidgeting, irritability, or lack of restraint

delirium, depression, hallucination, or paranoia

anxiety, apathy, or mood swings

tremor, weight loss, or impaired voice

What causes Huntington's Disease?

HD is caused by an inherited defect in a single gene.

HD is an autosomal dominant disorder, meaning that a person only needs one copy of the defective gene to develop HD

How a brain with and without HD looks like

This shows two different brains, one with HD and one without.

Top: with HD

Bottom: without HD

What happens to the brain when you have HD?

Huntington's Disease affects someone's ability to think, talk and move by destroying cells in the basal ganglia, the part of the brain that controls these capacities.
Treating Huntington’s Disease Patients