Down Syndrome

Trisomy 21

Causes of the Disorder and what chromosome is affected by the disorder

This is caused by autosomal nondisjunction. The chromosome that is affected by this disorder is chromosome 21, which in this case has three copies instead of two.

Are there prenatal tests for Down syndrome?

Yes, there are two types of tests. The screening test- include a combination of a blood test, and an ultrasound, which can bring a picture of the baby. The other test is Diagnostic tests. Diagnostic tests- Can usually detect if the child with have down syndrome or not. Both tests or anyone can predict the full impact of Down syndrome.

What are the symptoms of Down syndrome?

Some symptoms are: a flattened face, especially the bridge of the nose. Almond shaped eyes that slant up. Shorter in height as children and adults.

What population is affected by Down syndrome?

In the United States, 1 in every 800 people are affected.

Can anyone be a candidate for Down syndrome?

No, you don’t have a choice for the disorder, however, parents who decide to have their children earlier in their lifetime are less likely to have a Down syndrome child.

How is Down syndrome inherited? (Is it sex-linked, recessive, and/or dominant?)

Down syndrome is sex-linked.

What kind of medical assistance will the affected child need?

He/she will need medical assistance such as developmental interventions beginning during infancy. They may benefit from speech therapy, physical therapy and occupational therapy.

Will further assistance be needed, as the child grows older?

It depends, People born with Down syndrome can usually live independently.

What is the long-term outlook for the child?

Down syndrome is a lifelong condition. People with down syndrome will need extra attention and additional care. It is crucial that they get involved in the community as much as possible and seeing a healthcare provider as much also.

Are there any treatments or cures for Down syndrome?

There are a couple of procedures that can help down syndrome such as speech, occupational and physical therapy. There is not any cures or any other treatments.

Could Down syndrome have been prevented?

It could be prevented due to the age of the mother. Women who have children at a younger age are less likely to have mess ups with the chromosomes. If she decides to wait, the more chance that Down syndrome could occur.

Can this individual have children in the future?

They are still able to have children, however, only 15% - 30% with Trisomy 21 are fertile.

Will those children be affected?

There is about 50% chance of having child with Down syndrome.

What is the current status of research on Down syndrome?

Research and genetic testing continues to be done to find a cure however testing and funding continue to improve.

Is there a cure/new treatment coming soon?

There is no cure on the horizon "however the collection of DNA samples and cognitive profiles from individuals with Down syndrome will provide the basis for genetic analysis to identify targets for potential therapeutic interventions." (6)

Works cited page

"Active Research Projects." LuMind. N.p., n.d. Web. 30 Apr. 2015.

"Down Syndrome." Genetics Home Reference. N.p., n.d. Web. 30 Apr. 2015.

"Down Syndrome: Trisomy 21 - Causes, Symptoms and Risks." American Pregnancy Association. N.p., 25 Apr. 2012. Web. 30 Apr. 2015.

"Facts about Down Syndrome." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 20 Oct. 2014. Web. 30 Apr. 2015.