Paget's Disease
Alivia Lee
What is Paget's disease?
It is a disease that causes your bone to create new bone and remove old bone in an unbalanced way. This causes the bone to be enlarged, bent, or easily broken.
Causes
Viral
-can be formed by gradual viral infection present for many years before symptoms show.
Genetic
- most commonly there is a mutation with the gene that that is involved in regulating the function of osteoclasts (bone cells).
-genetic causes may or may not involve a family history of Paget's disease.
Symptoms (depending on affected area)
- skull- you may have symptoms including headaches, sagging face muscles, hearing problems, or loose teeth.
- spine-it may damage nerves and cause leg pain, numbness, or weakness.
Treatment
-if treatment is needed, the treatments are intended to control the disease activity and manage its complications.
-medications used are called bisphosphonates or injectable calcitonin.
Victims
-in most cases, Paget's disease affects adult, and older skeletal bones
-1% of adults in the U.S. have Paget's disease