Paget's Disease

Alivia Lee

What is Paget's disease?

It is a disease that causes your bone to create new bone and remove old bone in an unbalanced way. This causes the bone to be enlarged, bent, or easily broken.
Big image

Causes

Viral

-can be formed by gradual viral infection present for many years before symptoms show.


Genetic

- most commonly there is a mutation with the gene that that is involved in regulating the function of osteoclasts (bone cells).

-genetic causes may or may not involve a family history of Paget's disease.

Symptoms (depending on affected area)

  • skull- you may have symptoms including headaches, sagging face muscles, hearing problems, or loose teeth.
  • spine-it may damage nerves and cause leg pain, numbness, or weakness.

Treatment

-if treatment is needed, the treatments are intended to control the disease activity and manage its complications.

-medications used are called bisphosphonates or injectable calcitonin.

Victims

-in most cases, Paget's disease affects adult, and older skeletal bones

-1% of adults in the U.S. have Paget's disease