Gonen Ashkenasy
Ben-Gurion University of the Negev, Beer Sheva, Israel
The Systems Chemistry of Peptide Networks
Systems Chemistry aims to develop complex molecular systems showing emergent properties; i.e., properties that go beyond the sum of the characteristics of the molecular constituents of the system.(1,2) For the last 10 years our group has focused on the development of such systems using peptide-based replication networks. Two of the current challenges related to the design of complex chemical systems will accordingly be discussed: (i) evolving ‘self-synthesizing materials’ through utility of the replicating networks for various applications, such as catalysis and electron transfer, and (ii) design and analysis of chemical systems away from equilibrium by the incorporation of nonlinear processes and feedback loops. Future directions such as the search for synergism between molecules from different families (Nucleic acid, peptides, sugars etc.) will also be shortly highlighted.
Recent reviews:
G. Ashkenasy, T. M. Hermans, S. Otto, A. F. Taylor "Systems Chemistry" Chem. Soc. Rev. 2017.
Y. Bai, A. Chotera, O. Taran, C. Liang, G. Ashkenasy, D. G. Lynn “Achieving biopolymer synergy in systems chemistry" Chem. Soc. Rev. 2018
Event Information
Gonen Ashkenasy, The Systems Chemistry of Peptide Networks
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Wednesday, Jan 16, 2019, 11:00 AM
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