WANTED: Hepatitis B

Pathogen: Hepatitis B Virus (HBV)

Becky Keast

Mrs. Salemme

Honors Biology

17 March 2016


  • 42 nm long

    • 27 nm nucleocapsid core

    • Lipoprotein coat containing the surface antigen (HBsAg)

  • Contains partially double-stranded DNA
Big image


  • The hepatitis B virus targets liver cells
  • The virus can be transmitted sexually, perinatally, or through the sharing of drug-injection equipment
  • The virus can cause both acute and chronic disease


  • Victims mainly consist of humans ages 25 to 44
  • Individuals who have more than one sex partner, illegally inject drugs, and men who have intercourse with men are more likely to be diagnosed with HBV

  • An estimated 240 million people are chronically infected with hepatitis B

    • 20% to 30% of adults who are chronically infected will develop cirrhosis and/or liver cancer

    • 80–90% of infants infected during their first year develop chronic infections

    • 30–50% of children infected before the age of 6 years develop chronic infections

Hepatitis B Treatment Mode of Action Animation


  • Symptoms may include abdominal pain, dark urine, fever, joint pain, loss of appetite, nausea and vomiting, weakness and fatigue, and the yellowing of skin and whites of eyes

  • The virus attacks liver cells which causes inflammation within the liver

    • This can lead to cirrhosis, fibrosis, liver cancer or liver failure
  • HBV is 100 times more infectious than the AIDs virus


  • The hepatitis B virus is found in liver cells
  • The virus is most common in sub-Saharan Africa, East Asia, the Amazon Rainforest, and in certain parts of eastern and central Europe
  • The virus is also quite common in the United States


  • More than 780,000 people die every year due to complications of hepatitis B

    • HBV has a low mortality rate of about 0.7%

  • There is currently a safe and available vaccine for hepatitis B

    • The vaccine is effective 95% of the time

  • An acute hepatitis B infection normally clears up on its own through active immunity

  • Hepatitis B can also be prevented by using protection during sex and checking with those around you if they have been tested

    • Unfortunately, there is no cure for those with chronic hepatitis B except for having a liver transplant