Branson Moore

Famous Scientist

Hans A krebs

Hans A Krebs contributions to science were two specific thing. The Krebs Cycle and the citric acid cycle .The Krebs Cycle was discovered in 1937 . The krebs cycle occurs in a a aerobic organism that is part of the metabolic pathway where it converts with two things carbohydrates into water and carbon dioxide for energy in celluar respiration. It starts with glucose molecules and then that glucose molecule is broken up due to the process of a glycolsis into two pyruvic acids and two pyrvates . In 1937 Krebs demonstrated the existence of a cycle of chemical reactions this combines the end of sugar breakdown. The discovery of the Tricarboxylic acid cycle, which is central

to all metabolic reactions and the source of two-thirds of the food derived energy in higher organisms was of vital importance to a basic understanding of cell metabolism


Krebs then worked out the cyclic nature of the reactions. He noted that only certain organic acids were readily oxidized by muscle, and found that the oxidation of endogenous carbohydrate or pyruvate could be stimulated by a number of specific acids, all of which turned out to be substrates of the tricarboxylic acid cycle enzymes. by which ammonia is converted to urea in mammalian tissue the urea far less toxic than ammonia, is subsequently excreted in the urine of most mammals. This cycle also serves as a major source of the amino acid arginine.