Biology Research Project
what is Hemophilia?
- it affects your whole body ( your blood and circulatory system)
-unusual bleeding after vaccinations
- blood in your urine or stool
-pain, sweeping or tightness in your joints
- nose bleeds without a known cause
- in infants , unexplained irritability
- extreme fatigue
-painful, prolonged headache
-deficiency in plasma proteins or platelets
-genetic change (spontaneous mutation)
-Hemophilia A or B: its located on the x chromosome, and its passed from mothers to sons. Mothers are usually carriers of the defective gene. Can't be passed from father to son.
-Hemophilia C: it can be passed from either parent to either boys or girls.
- "If the gene is faulty, the result is hemophilia, unless there is a dominant, normal gene on a matching x chromosome. Hemophilia is a recessive trait."
-Mild Hemophilia A: slow injection of the hormone desmorpressin (DDAVP) into a vein.
-Moderate to severe Hemophilia A or B: infusion of recombinant clotting factor or clotting factor derived from donated human blood.
-Hemophilia C: Clotting Factor XI , plasma infusions
-Clot- Preserving Medications (antifibrinolytics)
-First Aid for Minor Cuts
- A blood test can show a clotting factor deficiency in children and adults.
- In pregnancy testing can be done to determine if the baby has hemophilia but there's a high risk factor.
-one-third of babies who are diagnosed with hemophilia have a new mutation not present in other family members.
- If there's a family history then counseling can be an option.
Effects on the Population
-Hemophilia occurs in 1 in every 5,000 male births
- About 20,000 males in the US are living with this disorder
- It affects people from all racial and ethnic groups
- only males can receive it , females are the carriers
-Hemophilia A is about four times as common as hemophilia B, and about half of those affected have the severe form.
- About 400 babies are diagnosed with hemophilia each year
What I Discovered
-Hemophilia only happens in males ( females is rare to have it)
- Its rare
-Mothers are only carriers
- Its inherited
- Its treatable but not curable
-It affects all types of males