The Invention of Chemotherapy
When was Chemotherapy "Invented"
The Inventor(s)- Sidney Farber- Alfred Gilman and Louis Goodman
*These People didn't invent chemotherapy, but they improved from what happened in WWII.
Sidney Farber started to mess with chemicals, after hearing what happened in WWII, to find a way to cure of some forms of cancer and other diseases.(picture one)
Alfred Gilman and Louis Goodman started to test mustard agents to treat lymphoma and other cancers in 1946.
Where the Invention was Being Worked on
History of Chemotherapy
Sidney Farber heard about the whole ordeal with the nitrogen mustard, and he proved that aminopterin reprieved children with acute leukemia. Aminopterin blocked a crucial reaction for DNA replication.
Alkylating agents damage the DNA to stop the reproduction of cancerous cells. Antimetabolites interfere with the DNA and RNA of cancerous cells to stop growth by taking the place of the normal building blocks of DNA and RNA. Anti-tumor antibiotics alter the DNA of the cancerous cells to stop multiplying/replicating. Anthracyclines are anti-tumor antibiotics. These are just some of the many different chemicals that doctors use in chemotherapy. All of these came from the idea in WWII.
The Impact on Society
Altman, Lawrence K. "Dr. Louis S. Goodman, 94, Chemotherapy Pioneer, Dies." The New York Times. The New York Times, 27 Nov. 2000. Web. 21 Sept. 2015.
Chemoterapy. Digital image. BeVeite. N.p., 19 May 2015. Web. 21 Sept. 2015.
Chemotherapy. Digital image. Mesothelioma Chemotherapy. About Mesothelioma, 17 Sept. 2015. Web. 18 Sept. 2015.
"Evolution of Cancer Treatments: Chemotherapy." Evolution of Cancer Treatments: Chemotherapy. American Cancer Society, 12 June 2014. Web. 18 Sept. 2015.
Mandal, Ananya. "History of Chemotherapy." News-Medical. N.p., 11 Dec. 2009. Web. 21 Sept. 2015.
Person in treatment of chemotherapy. Digital image. Treatment- Breast Cancer. N.p., n.d. Web. 22 Sept. 2015.
Sidney Farber. Digital image. Wikipediea. Wikipedia, n.d. Web. 21 Sept. 2015.
Yale University. Digital image. Zanda. N.p., n.d. Web. 21 Sept. 2015.