By Alyssa Machi
Hemophilia is a blood clotting disorder. This disorder was discovered by Dr. Judith Pool, in the 1960's. Those with Hemophilia do not have the proper amount of blood clotting factor. This is a single gene mutation occurring on the X chromosome, on F8 and F9 gene. This disorder will not will not affect an individuals life expectancy. However, hemophiliacs must be careful to avoid injury.
Those Hemophilia will bleed easily.
Those with Hemophilia do not have blood that clots correctly.
Symptoms and Side Affects
Depending on the severity of the disease, different side affects will occur. Common side affects are:
- Easy Bruising
- Very Bad Nosebleeds
- Heavy Bleeding after small Injuries
How is Hemophilia inherited?
Hemophilia occurs mostly in men. This occurs because a male will have an X and Y chromosome. A female has two X chromosomes, so if one of her chromosomes has this mutation, the other chromosome will take over. She will not have symptoms of Hemophilia, however she will be a carrier and her children may. Because a male only has one X chromosome, if the mutation occurs, he will show signs of Hemophilia. Altogether, this disease is inherited through either a carrier mother, or a father who has Hemophilia, however it is possible to develop this disease.
To diagnose Hemophilia:
Those who have symptoms of hemophilia will have a physical exam, and blood will be drawn to test for clotting factors.
There is no prevention of Hemophilia, however it can be treated. A patient will be injected with a clotting factor, either upon injury or every few weeks, months, etc. Because immunity can be developed, a patient may have to change medicines.
Those with Hemophilia will be treated with an injection.
- American Society of Hematology
- National Hemophilia Foundation