Cures

Type 1 Diabetes Cures

Research Question:

What are the cures for type 1 Diabetes that have been researched at Boston University? Not only did this question take me to Boston University research sites, it also took me to a CBS site for the University of Colorado and another website about a bionic pancreas written by Steven Russell. I hope you enjoy!!!

Backround Information

Definition of Type 1 diabetes:

Type 1 diabetes is a lifelong (chronic) disease in which there are high levels of sugar (glucose) in the blood.

See also:

Causes, incidence, and risk factors:

Type 1 diabetes can occur at any age. However, it is most often diagnosed in children, adolescents, or young adults.

Insulin is a hormone produced by special cells, called beta cells, in the pancreas. The pancreas is found behind your stomach. Insulin is needed to move blood sugar (glucose) into cells, where it is stored and later used for energy. In type 1 diabetes, beta cells produce little or no insulin.

Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. The body is unable to use this glucose for energy. This leads to the symptoms of type 1 diabetes.

The exact cause of type 1 diabetes is unknown. Most likely it is an autoimmune disorder. An infection or some other trigger causes the body to mistakenly attack the cells in the pancreas that make insulin. This kind of disorder can be passed down through families.

Source #1

This PDF file gives information on a bionic pancreas that Boston University has been researching. It is to be worn outside the body and it will have 3 different devices. The controller will be about the size of a smart phone. It will tell the pump what to do when it receives information from the disposable glucose sensor. The external pumps will deliver glucagon to diagnose for the low blood sugar and insulin to diagnose for the high blood sugar.


Author: Boston University

Site: http://www.bu.edu/bme/files/2012/12/Exhibit3.pdf

Organization: Boston University (college)

Date Created: not given

Medium: WEB, 20 May 2013

Source #2

The Artificial Pancreas that they are working on will be a closed loop. "The artificial endocrine pancreas automatically makes a new decision about insulin and glucagon dosing every five minutes." said Steven Russell. This artificial pancreas is being tested on people at Massachusetts General Hospital.


Author: Steven Russell

Site: http://artificialpancreas.org/

Organization: Boston University and Massachusetts General Hospital

Date Created: 2013

Medium: WEB, 21 May 2013

Source #3

The University of Colorado is doing research for cures of diabetes on mice. Right now, they are calling it "cd40 inhibitory peptide", but that will not be the name." 'It's having an impressive effect on mice. The drug is not only preventing mice from developing diabetes, it is also reversing the effects of diabetes in mice that already have the disease. That lasts for as long as we administer the drug', said Wagner." The next step is for FDA to approve it, then they will be allowed to do human trials. Wagner developed a blood test that predicts who will develop diabetes. when they find someone at risk of the disease during the blood test, they could administer the treatment. T Cells are also involved with multiple sclerosis, so maybe it could also cure that. "If all goes according to plan, the drug could reach the market in the next five to 10 years. Wagner said he's not sure if the treatment offers hope for adults with Type 2 Diabetes.


Author: not given

Site: http://denver.cbslocal.com/2012/03/09/cu-researchers-find-cure-for-type-1-diabetes-in-mice/

Organization: CBS News (local)

Date Created: 9 March 2012

Medium: WEB, 22 May 2013