Duchenne Muscular Dystrophy

DMD

What Causes This Disorder?

Duchenne Muscular Dystrophy was discrovered in the 1860's by the neurologist Guillaume Benjamine Amand Duchenne. Little was known about the disease until the 1980's. This disorder happens because a mutated gene fails to provide any or little functional dystrophin (protein that is effected in this disorder).

What chromosome and population is affected from this disorder?

The chromosome affected in this disorder is the X chromosome. This disorder is only found in males, but women can be carriers of this disorder. Duchenne affects 1 in every 3,500 to 6,000 male birth every year.

Tests and Symptoms

Prenatal test for this disorder are Genetic testing. This type of test can help identify the cause of muscle problems. It can also determine prenatal diagnosis. There are a lot of symptoms for this disorder. One being that there might be frequent falling, difficult to get up from a sitting position, walking on toes, large calf muscle, and trouble running and jumping. Most people with this disorder will be in a wheelchair before they are 16.

How is it Inherited? Can this disorder be prevented?

This disorder is inherited usually from his mother. This disorder is inherited through the X chromosome. this disorder is usually only in males. Duchenne Muscular Dystrophy can not be prevented becuase it is a genetic disorder.

Options for the children

The kind of assistance the child will need is they will need a wheelchair before the age of 16. The kid affected needs several check ups to monitor their muscle heath. As the child gets older the medical assistance will continue, it will be more often. They now have to check for heart problems and lung issues. Muscular Dystrophy is a long-term disorder must kids will have heart or lung problems depending of the type. A person with DMD can have children, but a lot of the time the kid will also have DMD.

Treatments or Cures?

There are no cures for muscular dystrophy because of it being a genetic disorder. The treatments can be steroids to slow down the muscle strength loss. Stem cells and gene therapy can be used in the future. There are no new cures coming to help people affected but everyday someone is working on a new treatment. The current status is that only 1 in every 3,500 males are affected.