General information

Moebius syndrome is a rare neurological disorder that can be present at birth. If you dont have it at birth then you will not have it at all. It primarily affects the 6th and 7th cranial nerves, leaving those with the condition unable to move their faces and they can’t even smile, frown, suck, grimace or blink their eyes and unable to move their eyes up and down.


  • Lack of facial expression; inability to smile
  • Feeding, swallowing and choking problems
  • Keeping head back to swallow
  • Eye sensitivity due to inability to squint
  • Motor delays due to upper body weakness
  • Absence of lateral eye movement
  • Lack of facial expression; inability to smile
  • Feeding, swallowing
These are just some of the symptoms, there are tons more

Inheritance pattern

The exact incidence of the syndrome is unknown, researches have estimated that the syndrome only affects 1 in 50,000 to 1 in 500,000 newborns. So moebius syndrome is autosomal recessive

Ways it can be treated

Infants sometimes require special bottles or feeding tubes to maintain sufficient nutrition. Strabismus (crossed eyes) is usually correctible with surgery. Children with Moebius syndrome usually benefit from physical and speech therapy to improve their motor skills and coordination, and to gain better control over speaking and eating.

Limb and jaw deformities can be improved through surgery. In addition, plastic reconstructive surgery of the face can offer benefits in individual cases.

In that surgery, nerve and muscle transfers to the corners of the mouth have been performed to provide an ability to smile.