CRI DU CHAT DISORDER

By: Brandee Albertson

What is Cri du chat?

Cri du chat is a rare genetic disorder cause by a missing part of chromosome 5. The cri du chat is a rare genetic condition Which is cause by the deletion of the chromosome. Babies who have this syndrome mostly has a high pitch cry that sounds like a cat. Some children with cri du chat syndrome are born with a heart defect.

What are the symptoms of cri du chat

The symptoms vary among individuals!!!


* Cat-like cry in infants * Severe mental retardation * Severe growth retardation

* Small head * Reduced muscle tone * Round face

* Low set deformed ears * Wide-set eyes * Epicanthic folds

* Respiratory problems * Low birth weight

Cause of cri du chat

This disorder is cause by a deletion of the end of the short arm of chromosome 5. The body differs for individuals the disorder does not have a specific part of the body it affects. The disorder is an abnormal larynx development, one of many symptoms associated with this disorder.

Is Cri du chat syndrome inherited?

The disorder is not inherited. The chromosomes break occurs while the sperm or egg is developing. Deletion occurs most often as a random event during the formation. About 10 percent of people with cri du chat syndrome inherit the chromosome with a deleted segment from an unaffected parent. In many cases the male sperm has the chromosome carrying the deletion rather than the female egg.

How is cri du chat syndrome diagnose and what is the treatment

There is no specific treatment. Some individuals take therapy to improve their language skills and to help them develop as normally as possible. Most often doctors can identify cru du chat when the baby lets out a cat-like cry. There is also a test for cri du chat while the baby is still not born. They can test a tiny sample of tissue from the outside of the sac where the baby develops.

How many and what type of people are likely to have cri du chat



Cri-du-chat syndrome occurs in an estimated 1 in 20,000 to 50,000 newborns. This condition is found in people of all ethnic backgrounds. Both children and adults with the syndrome cri du chat are usually are nice and glad (happy) and they love social interaction. People with cri du chat normally don't have history of the condition in their family.