Down Syndrome

By: Zakaria A., Jonah H., Jacob N, and Mia H.

The Team

Zakaria- Graduated from TCU with a PhD, he has been working to find a cure for Down Syndrome for 10 now. He has worked in St. Louis Hospital for 5 years so far.
Jonah- Graduated from John Hopkins School of Medicine with a Md in, always had an interested in D.S, and working at Boston's Children Hospital.
Jacob- Graduated from Yale with a PhD, has a child that has Down Syndrome since birth, and is currently working at Texas Children's Hospital.
Mia- Graduated from Harvard Medical Md/PhD Program with a Md, she has been working on how Down Syndrome is caused for 7 years now, and is currently working at Packard Children's Hospital for 3 years and going strong.

What is Down Syndrome?

Down Syndrome is caused by an error in the cell division process. D.S has many different types. They are called Trisomy 21, Mosaicism, and Translocation. Trisomy 21 is the most common out of all the different types where you have an extra chromosome in number 21. Mosaicism is when 2 cells are from 2 different genetic types. Translocation is where part of the chromosome is relocated to another chromosome or the same one, but in a different spot. John Langdon Down was the first person to learn about D.S in 1866.


We are trying to find the cause and cure for Down syndrome.
We want to be able to stop down syndrome from generation to generation.


We are trying to make people see that D.S is important and a big thing that some families have to deal with.

We want to find a cure for Down Syndrome to give every kid a normal life and normal opportunities to see the world and not have to deal with so many problems.


Down Syndrome is the least funded major genetic condition since there isn't much about the topic. Some conditions that come with D.S is heart defects, sleep apnea, and Alzheimer's. By trying to stop D.S would have less people having these problems would be very good.


Rent Workspace- $3,000 a month
Workers- $70,000-$120,000 a year
Tools- $75,000
Experts-$100 an hour
Test Subjects-$350 a day
Total Estimate per Year: $747,050


  • We will use the resources at a college research hospital that already has some experience in studying Down’s Syndrome Children or experience with other genetic conditions. We'll ask a group of the Medical Students who may be studying genetics for ideas on how to identify the cause. Based on current research there is no central database or information of people with Down’s syndrome who may want to participate in clinical trials or studies.
  • We will have a soft of carnival with booths that have D.S symptoms to see if they have D.S, then we will contact them later to talk to or even test if they are willing to.


About 400,000 people of all kinds everywhere have D.S. Even though there isn't much about it, they will live long lives as long as they are in good environments surrounded with good people. Getting more people involved into the Down Syndrome is really important to have more and more people that know, then it could expand to get even bigger and grow in knowledge.