The HPV Virus

Emma Gable

What is HPV?

HPV is a non-crueable disease, that spreads by touch, or passed down genorations. This virus causes warts and Cervical cancer.

Causes

This virus is primarily transferred by skin-to-skin contact.It occurs when the virus enters your body through a cut, abrasion, or small tear in your skin. Most of the time, HPV is spread through sexual activity and genital contact.

How Virus Replicates

This virus uses the Lysogenic cycle to grow or expand.

Symptoms and Treatments

Many people with HPV don't develop any symptoms of the virus but they can still affect others through sexual contact. The symptoms may include warts on the genitals or near surrounding skin. Cervical cancer usually does not have symptoms until it is quite advanced, it becomes very serious and hard to treat.

The virus can't be cured, but and be treated. A vaccine that prevents the HPV strains most likely to cause genital warts and cervical cancer is recommended for boys and girls. In the United States we use a Bivalent vaccine Cervarix. This vaccine mainly focuses on the warts and cancer. Also, they can remove the warts by freezing or digging them out or the will leave on their own.

Immune Cells Involved in Immune Response

The interferon response for HPV infection, a key antiviral defence mechanism , is actively suppressed with the E6 and E7 proteins of the high risk HPVs inhibiting the interferon receptor signalling pathways and the activation of the interferon response genes. The E7 proteins downregulate TLR9 and overall HPV effectively evades the innate immune response delaying the activation of adaptive immunity.


Preventions

There are many cautions or preventions you can take in order to aviod HPV. First adopt a healthy diet to boost your immune system for fighting off the infection. Second stay abstinent, third get the HPV vaccine (before becoming sexually active). Last, but least limit your number of sexual partners.