Augmentin Order Form
Antacids, glucosamine, laxatives, aminoglycosides slow down and reduce absorption; ascorbic acid increases absorption. Bacteriostatic antibiotics (macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides) have an antagonistic effect. Increases the effectiveness of indirect anticoagulants (suppressing the intestinal microflora, reduces the synthesis of vitamin K and the prothrombin index). With the simultaneous administration of anticoagulants, it is necessary to monitor blood coagulation. Reduces the effectiveness of oral contraceptives, drugs, during the metabolism of which PABA is formed, ethinyl estradiol - the risk of bleeding “breakthrough”. Diuretics, allopurinol, phenylbutazone, NSAIDs and other drugs that block tubular secretion increase the concentration of amoxicillin (clavulanic acid is excreted mainly by glomerular filtration). Allopurinol Increases Risk of Skin Rash. A description of the active substances of the drug is provided. The scientific information provided is generalized and cannot be used to decide on the possibility of using a specific drug.
The pharmacokinetic parameters of amoxicillin and clavulanic acid were obtained in different studies in healthy volunteers after fasting: 1 tablet of Augmentin buy augmentin 875 125 mg (250 mg / 125 mg), or 2 tablets of Augmentin (250 mg / 125 mg), or 1 tablet of Augmentin (500 mg / 125 mg ), or amoxicillin (500 mg), or clavulanic acid (125 mg) separately. When using Augmentin, plasma concentrations of amoxicillin are similar to those with oral administration of amoxicillin in equivalent doses.
Amoxicillin and clavulanic acid dissolve well in aqueous solutions with physiological pH and, after ingestion of Augmentin, are rapidly and completely absorbed from the gastrointestinal tract. Augmentin active substance absorption is optimal when taken at the beginning of a meal. The therapeutic concentrations of both active substances are determined in various organs, tissues and body fluids (including in the lungs, abdominal organs; adipose, bone and muscle tissues; pleural, synovial and peritoneal fluids; in skin, bile, urine, purulent discharge, sputum, in interstitial fluid).
Plasma protein binding is moderate: 25% for clavulanic acid and 18% for amoxicillin. Amoxicillin (like most penicillins) is excreted in breast milk. Traces of clavulanic acid have also been found in breast milk. With the exception of the risk of sensitization, no other adverse effects of amoxicillin and clavulanic acid on the health of breast-fed infants are known.. In experimental animal studies, it has been shown that amoxicillin and clavulanic acid cross the placental barrier. However, no impaired fertility or adverse effects on the fetus. In animal studies, no cumulation of Augmentin ingredients in any organ was found. Amoxicillin is excreted mainly by the kidneys, while clavulanic acid through both renal and extrarenal mechanisms. After a single oral administration of one tablet of 250 mg / 125 mg or 500 mg / 125 mg, approximately 60-70% of amoxicillin and 40-65% of clavulanic acid are excreted unchanged in the urine during the first 6 hours. About 10-25% of the initial dose of amoxicillin is excreted in the urine in the form of inactive penicilloic acid. Clavulanic acid in the human body undergoes intensive metabolism with the formation of 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid and 1-amino-4-hydroxy-butan-2-one and excreted in urine and feces.
This type of urethritis is distinguished by white foamy discharge from the urethra. Mild itching may be observed. The development of the disease begins 5-15 days after infection. Chronic trichomonas urethritis can be complicated by trichomonas prostatitis. Complication is observed in 15-20% of cases. To prevent re-infection, both partners are treated simultaneously. If necessary, you can repeat the course.
Nutrition and nutritional supplements for the treatment of urethritis. Appropriate nutrition, the use of herbs, homeopathic remedies, and acupuncture procedures can be effective in combating infection, relieving pain, and strengthening the urinary system. http://www.webmd.com/drugs/2/drug-4333-5050/augmentin-oral/amoxicillin-clavulanic-acid-suspension-oral/details Always tell your doctor about the herbs and supplements you are using. The following tips can help reduce the symptoms of urethritis: Eat foods that are high in antioxidants, including fruits, berries, and vegetables (such as blueberries, cherries, pumpkins, tomatoes, bell peppers). - Try to eliminate potential food allergens. To do this, you may have to take a test to check your food sensitivity. - Limit the consumption of red meat, give preference to leaner meats, fish or beans are also good for protein. - If possible, exclude refined products such as white bread, sugar, pasta. - It is important to use healthy edible oils, such as olive or vegetable. - Reduce or eliminate the use of commercial bakery products (cookies, cakes, crackers, french fries, donuts, margarine) due to their trans-fatty acids. - Try to completely abandon the use of coffee, tobacco, alcoholic beverages and other stimulants. - Use at least 5 to 8 glasses of filtered water per day. - Do not forget to do physical exercises.