Non-Melanoma Skin Cancer

Sarah Wilson & Jenna Sipos

Information about Non-melanoma Skin Cancer

  • Skin cancer is the most common cancer type
  • It makes up 50% of all cancer cases and is split up into two groups: nonmelanoma and melanoma
  • Nonmelanoma is much more common and is more easy to treat

Definition of non-melanoma skin cancer

Non-melanoma skin cancer is the abnormal growth of skin cells in the epithelial layer of the skin.
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How prevalent is nonmelanoma skin cancer?

Every year in America there are 5.4 million cases of non-melanoma skin cancer. Skin cancer is by far the most common of the cancers. Non-melanoma cancer is more common than melanoma.
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How is non-melanoma skin cancer diagnosed?

For most cases of skin cancer a biopsy is the only way to get accurate results. A biopsy is the removal of a small amount of tissue for close examination under a microscope. The sample is then analyzed by a pathologist to determine whether the person has or has not skin cancer.

What are the causes of nonmelanoma skin cancer?

The causes of non-melanoma cancer are overexposure to the sun’s UV rays, tanning beds, excessive x-ray exposure, also repeated exposure to chemicals such as coal tar, creosote, arsenic and radioactive substances like radium.
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  • The first step in treating skin cancer is to stage it which is seeing how far it has spread. It have five stages: O, I, II, III, IV.
  • O is the easiest curable meaning it has not spread and lies right below the tissue and IV is the hardest to cure because it has moved into organs.
  • More ways specifically for nonmelanoma is to get surgery, radiation which uses high energy to kill the cancer cells, and chemotherapy which is anticancer drugs that can be injected, taken as a tablet, or even used as a cream directly on the skin.


  • Bump or sore could be a symptom
  • Basal cell carcinomas on head, neck, or chest
  • Squamous cell carcinomas head,neck,hands,arms,genital region, or on/in scars or sores
  • Could also be normal looking skin thats why its important to check
Non-Melanoma Skin Cancers | Skin Cancer

Cellular And Molecular Levels

  • UVB radiations damages DNA in skin cells causing lesions or photoproducts

  • If not repaired lesions will turn into skin cancer

  • Cancer cells affect a DNA’s growth, replication, and ability to live and intrude tissue located around

  • 1 cancer cell diving into 2 by ATP

  • Glucose gets in cell from bloodstream

  • Some glucose converted into pyruvate

  • Pyruvate gets in mitochondria

  • Once is mitochondria pyruvate starts 2 sequential chemical reactions

that creates most ATP in cells

  • Cell divides

Sources Used