Cystic Fibrosis

A genetic disorder (CF)

By: Olivia Bartkowiak

What causes Cystic Fibrosis? What is it?

Mucus clogs organs including your lungs, liver, and pancreas. A defective gene causes the secretions to become thick and sticky. People with Cystic Fibrosis tends to have a higher than normal level of salt in their sweat. They have a defective gene on chromosome 7 called CFTR. The protein is produced by this gene which normally helps salt move in and out of the cells.

How do you get CF?

People with Cystic Fibrosis inherit a defective gene on chromosome 7 called CFTR (Cystic Fibrosis Trans-membrane Conductance Regulators). The protein is produced by this gene, which normally helps salt move in and out of cells.

Signs and Symptoms

  • A persistent cough that produces thick spit and mucus
  • Wheezing
  • Breathlessness
  • A decreased ability to exercise
  • Repeated lung infections
  • Inflamed nasal passages or stuffy nose
  • Poor weight gain and growth
  • Intestinal blockage, particularly in newborns
  • Severe constipation
What is cystic fibrosis? Animation

What's the video about?

Cystic Fibrosis is a genetic disorder (gf) which causes our body to create mucus that covers our organs. There are 30,000 people across the country and 70,000 in the world. Cystic Fibrosis is not contagious and you only can get it when your born.

Frequency

  1. 1 in 2,500 Caucasian infants in the US is affected with Cystic Fibrosis.
  2. There are 30,000 people across the country with Cystic Fibrosis.
  3. There are 70,000 people in the world with Cystic Fibrosis.

Cures

Antibiotics: Treat and prevent long infections mucus, and help you cough up mucus, improves long infections.


Oral Pancreatic Enzymes: Help your digestive tract absorb nutrients.


Bronchodilators: Help keep air ways open by relaxing the muscles around your bronchial tubes.

Scientists Involved

  • 1953 Paul di Sant' Agnese revealed the increased salt content of sweat in people with Cystic Fibrosis.
  • 1964 Cystic Fibrosis Research Foundation Trust was established.

Important to science

This topic is important to science, because it is a genetic disorder that is very serious, and can be fatal. It is a topic that is currently being investigated to try to find a precise cure for it.

Sources

  1. Biology Book
  2. MayoClinic.org
  3. LearnGenetics.edu
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