Survanta (Trade Name)

beractant (intratracheal suspension) (Generic name)

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What is used for?

This drug is a lung surface medication that acts as "surfactant". It helps the lungs of a premature infant function normally. Beractant is like the natural fluid in the lungs that maintain breathing effectively. It is given intratracheal via a 5 French catheter down the endotracheal tube directly into the lungs. All of the lung lobes must receive the medication so the infant needs to be turned according to instructions.

The Pharmacokinetics of beractant:

This is a sterile non-pyrogenic pulmonary surfactant from a bovine lung extract containing phospholipids, neutral lipids, fatty acids and surfactant-associated protein's to mimic surface-tension lowering properties of natural lung surfactant. (1) Provides 25mg/mL phospholipids, 0.5-1.75 mg/mL triglycerides, 1.4-3.5 mg/mL free fatty acids and less than 1.0 mg/mL protein (1) . Suspended in 0.9 % Sodium Chloride solution, and heat sterilized. (1) The protein's consist of 2 hydrophobic low molecular weight surfactant-associated protein's commonly known as SP-B and SP-C. (1) It however, does not contain any hydrophilic, large molecular weight surfactant associated protein known as SP-A. (1)

Precautons with beractant:

Moist breath sounds or Rales can occur after administration. There is also an increased risk for nosocomial sepsis in the beractant treated infant. Respiratory Therapists should watch for compliance levels on ventilated babies as it can change quickly. . Trained Personal should be with the infant during treatment with Beractant, trained in intubation and mechanical ventilator management. The medication should never be shaken. It should be swirled in the vial and then dosed via syringe for intratracheal delivery. This medication should always be protected from light.

Side effects with beractant:

A common side effect with this drug is bradycardia and oxygen desaturation. These problems are the most serious. Other side effect include hypercarbia, hypocarbia, hypertension, endotracheal tube blockage, Pale skin, apnea, less urination than normal, blood in the urine, feeding or bowel issues and bleeding around the endotracheal tube.(2)

Drug interactions:

There are no known drug interactions for this medication at this time. (3)

Contraidications:

There are no known contraindications at this time.

References:

1.www.RXlist.com/survanta-drug/patient. Accessed February 1, 2016.

2. Survanta.com/index.cfm. Copyright AbbVieInc.2013. Accessed Feb1, 2016.

3. US Food and Drug Administration. Drug @ FDA Approved Drug Products DataBase. Accessed Feb. 1, 2016.

4. Final photo courtesy of:

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